Thus far, all studies that have found a direct link between ginger or its derived compounds and testosterone were in vivo system studies, and no human studies were conducted in this specific research context. Various studies have measured testicular weight as a marker for reproductive capability following dietary supplements. It is well-known that the vasodilation effect of NO increased blood flow in the blood vessels 58,59. In fact, several studies have introduced the antihyperglycemic effect of dietary ginger on blood glucose 49,50,51.
Another study found that ginger increased testicular weight along with serum cholesterol and testosterone levels in healthy rats after daily intake for 8 days. Adding ginger extract significantly increased testicular and epididymal tissue weight, serum testosterone levels, total sperm count and their motility in semen. Zahedi et al. (2012) examined the effect of ginger on the toxic effects of gentamicin on sperm fertility parameters and showed that ginger could eliminate the toxic effects of gentamicin and significantly increase serum testosterone levels in rats.
However, when ginger-derived compounds like zingerone, geraniol, and 6-gingerol were administered separately, they did not significantly affect testosterone levels in diabetic rats. Numerous in vivo studies have explored the potential link between ginger and testosterone levels. Ginger supplementation has been found to increase NO production, which can enhance testosterone levels. Studies have shown that men with diabetes and suboptimal blood sugar levels are at increased risk of developing testosterone deficiency in the future. Ginger has also been found to regulate blood glucose levels, which is important for maintaining healthy testosterone levels.
Several investigators have tried to boost semen quality indicators in poultry using plant materials with antioxidant properties with mixed results (Khan et al., 2012; Nahed et al., 2014; Neuman et al., 2002; Ommati et al., 2013). Naturally, the sperm antioxidant defense action against ROS attack is weak, but the seminal antioxidant defense activity tends to boost defense against ROS (Zini et al., 2009). Traditional semen quality assessment methods demand the calculation of sperm motility, viability, concentration and morphology of spermatozoa as well as semen volume and semen colour. Due to this preventive effect on the sperm parameters it seemed that it could be effective for treatment of diabetic rats (Nassiri et al., 2009).
Another threat that may be minimized by ginger consumption is the growth of cancer cells and the aging and death of healthy cells. This research demonstrates that ginger contains precisely this combination of properties, making it uniquely suited for addressing male reproductive challenges. Among infertile marriages, approximately 50% of cases involve male factors, making treatments targeting men’s reproductive health critically important. The study documented a dramatic 55.9% decrease in malondialdehyde (MDA)—a marker of oxidative damage—in semen samples after ginger treatment. Sperm viability improved by 40.7%, and normal sperm morphology increased by 17.1%. Sperm count increased by 16.2%, while sperm motility—the ability of sperm to move effectively—jumped by an astounding 47.3%.
Alongside these volatile oils, ginger is rich in antioxidant compounds like vitamin C, vitamin E, beta-carotene, lutein, lycopene, quercetin, genistein, and tannin. Additionally, ginger has shown potential as an aphrodisiac and may have positive effects on erectile function. Understanding the potential of ginger as a natural testosterone booster could provide valuable insights for those seeking to optimize their hormonal balance and overall well-being. However, the effect of ginger on testosterone is not yet confirmed in humans. To achieve this contribution, we searched the PubMed, Scopus, and Web of Science databases for English language articles (full texts or abstracts) from November 1991 through August 2018 using the keywords "ginger" and "Zingiber officinale" versus "testosterone".
In conclusion, changes in lifestyle, changes in food culture, environmental pollution and excessive use of chemicals in the food industry and animal husbandry can increase the risk of oxidative stress on physiological process. Also, adding high concentrations of the ginger extract significantly reduced sperm abnormalities. The researchers recommended that ginger in the diet improves the quality of semen, especially in commercial chickens (Akhlaghi et al., 2014).

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